The meeting of the German Society of Human Genetics (gfh) was held in Weimar, Germany this week and of course the attendees had the opportunity to visit the joined booth of MetaSystems and MetaSystems Probes. Main topics of the exhibition have been the latest advancements of the Neon case and imaging platform and RapidHyb, the revolutionary fast hybridization times of MetaSystems Probes' FISH probes.
Break Apart Probe
- Order Number
- Package Size
- 100 µl (10 Tests)
The t(11;14)(q13;q32) chromosomal translocation is the hallmark of mantle cell lymphoma (MCL) and is found in approximately 30 % of multiple myeloma (MM) tumors with a 14q32 translocation. Variant translocations can fuse CCND1 also with other genes, such as IGK or IGL.
- Multiple Myeloma and Plasma Cell Neoplasms (MM)
- Non-Hodgkin Lymphomas (NHL)
Two green-orange (2GO) fusion signals representing the two normal CCND1 loci.
Aberrant Cell (typical results):
One green (1G), one orange (1O), and one green-orange (1GO) fusion signal, indicating a chromosome break in the CCND1 locus.
- Vandraager et al (1997) Blood 89:349-350
- Fonseca et al (2002) Blood 99:3735-3741
- Wlodarska et al (2004) Leukemia 18:1705-1710