XL t(1;19) PBX1/TCF3 DF

Translocation/Dual Fusion Probe

Order Number
D-5153-100-OG
Package Size
100 µl (10 Tests)
Labels
  
Chromosomes
119

Description

XL t(1;19) PBX1/TCF3 DF

XL t(1;19) PBX1/TCF3 DF consists of an orange-labeled probe hybridizing to the PBX1 gene region at 1q23.3 and a green-labeled probe hybridizing to the TCF3 (E2A) gene region at 19p13.

Please note that this product is not classified as an IVD product in the EU according to the REGULATION (EU) 2017/746 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 5 April 2017 on in vitro diagnostic medical devices and repealing Directive 98/79/EC and Commission Decision 2010/227/EU. It is marked as for ´Research Use Only´ (RUO).

Probe maps are created in accordance with the intended purpose of the product. Solid colored bars do not necessarily indicate that the probe fully covers the indicated genomic region. Therefore, caution is advised when interpreting results generated through off-label use. Probe map details based on UCSC Genome Browser GRCh37/hg19. Map components not to scale. Further information is available on request.

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Images

XL t(1;19) PBX1/TCF3 DF

XL t(1;19) PBX1/TCF3 DF hybridized to lymphocytes. Two normal interphases are shown.

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Expected Patterns

Expected Pattern 1

Normal Cell:
Two green (2G) and two orange (2O) signals.

Expected Pattern 2

Aberrant Cell (typical results):
One green (1G), one orange (1O), and two green-orange fusion (2GO) (adjacent green and orange) signals.

Please note that green signals tend to split.

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