The XL Acro-p probe contains sequences which specifically hybridize to the short (p) arm of all human acrocentric chromosomes. The XL Acro-p FISH probe may replace conventional silver staining used to stain the NOR regions.

Please note that this product is not classified as an IVD product in the EU according to the REGULATION (EU) 2017/746 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 5 April 2017 on in vitro diagnostic medical devices and repealing Directive 98/79/EC and Commission Decision 2010/227/EU. It is marked as for ´Research Use Only´ (RUO).

Probe maps for selected products have been updated. These updates ensure a consistent presentation of all gaps larger than 10 kb including adjustments to markers, genes, and related elements. This update does not affect the device characteristics or product composition. Please refer to the list to find out which products now include updated probe maps.

Probe map details are based on UCSC Genome Browser GRCh37/hg19, with map components not to scale.

XL Acro-p was hybridized to normal lymphocytes. A metaphase with orange signals at band p12 of all acrocentric chromosomes (13, 14, 15, 21 and 22) is shown.