XL Acro-p

Order Number
D-5440-050-OR
Package Size
50 µl (5 Tests)
Labels
 
Chromosomes
1314152122

Description

XL Acro-p

The XL Acro-p probe contains sequences which specifically hybridize to the short (p) arm of all human acrocentric chromosomes. The XL Acro-p FISH probe may replace conventional silver staining used to stain the NOR regions.

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Clinical Details

Variations in length of stalks and satellites of human acrocentric chromosomes are considered as normal variable chromosome features. However, cryptic translocations can result in unbalanced karyotypes but might be misinterpreted as common acrocentric short arm polymorphisms.

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Images

XL Acro-p

XL Acro-p was hybridized to normal lymphocytes. A metaphase with orange signals at band p12 of all acrocentric chromosomes (13, 14, 15, 21 and 22) is shown.

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Literature

  • Benzacken et al (2001) Prenat Diagn 21:96-98

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