The XL Acro-p probe contains sequences which specifically hybridize to the short (p) arm of all human acrocentric chromosomes. The XL Acro-p FISH probe may replace conventional silver staining used to stain the NOR regions.

Please note that this product is not classified as an IVD product in the EU according to the REGULATION (EU) 2017/746 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 5 April 2017 on in vitro diagnostic medical devices and repealing Directive 98/79/EC and Commission Decision 2010/227/EU. It is marked as for ´Research Use Only´ (RUO).

Probe maps are created in accordance with the intended purpose of the product. Solid colored bars do not necessarily indicate that the probe fully covers the indicated genomic region. Therefore, caution is advised when interpreting results generated through off-label use. Probe map details based on UCSC Genome Browser GRCh37/hg19. Map components not to scale. Further information is available on request.

XL Acro-p was hybridized to normal lymphocytes. A metaphase with orange signals at band p12 of all acrocentric chromosomes (13, 14, 15, 21 and 22) is shown.