About 100 guests from 36 countries met on the XVIII. MetaSystems Distributor Meeting (DM) in November to exchange experiences and to get to know new trends and developments at MetaSystems.
XL 21q22 / XCP 21
- Order Number
- Package Size
- 50 µl (5 Tests)
The XL 21q22/XCP 21 is a combination of a whole chromosome paint 21 in green with an orange labeled locus-specific probe for 21q22. This probe allows analysis of copy numbers and structural aberrations of chromosome 21 on metaphase chromosomes.
Probe maps are created in accordance with the intended purpose of the product. Solid colored bars do not necessarily indicate that the probe fully covers the indicated genomic region. Therefore, caution is advised when interpreting results generated through off-label use. Probe map details based on UCSC Genome Browser GRCh37/hg19. Map components not to scale. Further information is available on request.
This probe is not intended for use in analysis of trisomy 21 in prenatal diagnosis.
XL 21q22/XCP 21 hybridized to normal human metaphase spreads will result in green signals along the entire length of chromosome 21 combined with orange signals at 21q22 (Down Syndrome Critical Region 4).
A translocation with involvement of chromosome 21 will result in a split of a green signal. In this case, the green signal will be partially visible on the der(21) and the respective partner chromosome of the translocation. Depending on the localization of the breakpoint on the der(21), the signal of the locus-specific probe remains on the der(21) or will be observed on the translocation partner.
Certificate of Analysis (CoA)or go to CoA Database