Past event in Netherlands from Mar 19 to Mar 21, 2025
XA 13/21
Aneusomy Probe
- Order Number
- D-5602-100-OG
- Package Size
- 100 µl (10 Tests)
- Regulatory Status
- IVDR
IVDR Certification
This probe is IVDR-certified in compliance with the Regulation (EU) 2017/746 for in vitro diagnostic medical devices (IVDR).
MetaSystems Probes has already certified a wide range of FISH probes, according to IVDR.
This product may not be available in all countries outside the European Union.
The XA 13/21 enumeration probe is a qualitative, non-automated test for the detection of copy number variations of chromosome 13 and chromosome 21 by fluorescence in situ hybridization (FISH). The product is intended for prenatal testing of pregnancies at risk for trisomy 13 and trisomy 21 on methanol/acetic-acid fixed uncultured amniocytes.
The XA 13/21 enumeration probe consists of a green-labeled probe hybridizing to the RB1 gene region at 13q14.2 and an orange-labeled probe hybridizing to the DSCR4 gene region at 21q22.1-22.2.
Probe maps for selected products have been updated. These updates ensure a consistent presentation of all gaps larger than 10 kb including adjustments to markers, genes, and related elements. This update does not affect the device characteristics or product composition. Please refer to the list to find out which products now include updated probe maps.
Probe map details are based on UCSC Genome Browser GRCh37/hg19, with map components not to scale.
XA 13/21 was hybridized to normal lymphocytes. Interphase nuclei with two orange and two green signals each are shown.
Normal Cell:
Two green (2G), two orange (2O) signals.
Aberrant Cell:
Three green (3G) and two orange (2O) signals.
Aberrant Cell:
Two green (2G) and three orange (3O) signals.
Tumour Genetics Symposium 2025
Past event in Germany from May 8 to May 10, 2025
Meet our colleagues in Leipzig, Germany!
European Cytogenetics Conference
Past event in Belgium from Jun 29 to Jul 1, 2025
Meet our colleagues in Leuven, Belgium!
